Childhood psychosocial factors and coronary artery calcification in adulthood: The cardiovascular risk in young finns study

M Juonala; L Pulkki-Råback; M Elovainio; C Hakulinen; CG Magnussen; MA Sabin; DP Burgner; DL Hare; O Hartiala; H Ukkonen; A Saraste; S Kajander; N Hutri-Kähönen; M Kähönen; I Rinta-Kiikka; T Laitinen; S Kainulainen; JSA Viikari; OT Raitakari

Journal article

Childhood psychosocial factors and coronary artery calcification in adulthood: The cardiovascular risk in young finns study

M Juonala, L Pulkki-Råback, M Elovainio, C Hakulinen, CG Magnussen, MA Sabin, DP Burgner, DL Hare, O Hartiala, H Ukkonen, A Saraste, S Kajander, N Hutri-Kähönen, M Kähönen, I Rinta-Kiikka, T Laitinen, S Kainulainen, JSA Viikari, OT Raitakari

JAMA Pediatrics | Published : 2016

DOI: 10.1001/jamapediatrics.2015.4121

Abstract

IMPORTANCE There is increasing evidence supporting the importance of psychosocial factors in the pathophysiology of atherosclerotic disease. They have been shown to be associated with the population attributable risk formyocardial infarction. OBJECTIVE To determine if a score of favorable childhood psychosocial factors would be associated with decreased coronary artery calcification in adulthood. DESIGN, SETTING, AND PARTICIPANTS The analyseswere performed in 2015 using data gathered in 1980 and 2008 within the longitudinal Cardiovascular Risk in Young Finns Study. The data source consisted of 311 individuals who had psychosocial factors measured at ages 12 years to 18 years and coronary art..

View full abstract

University of Melbourne Researchers

Matt Sabin Author

David Burgner Author

David Hare Author

Related Projects (1)

PRACTITIONER FELLOWSHIP - PROF DAVID HARE

As Director of Research in the Department of Cardiology, Prof Hare supervises a number of research groups, a major one being a “Psychosocial..

Grants

Awarded by Suomen Lääketieteen Säätiö

Funding Acknowledgements

This study was financially supported by the Academy of Finland (grants 126925, 121584, 124282, 129378, 117797, 265977, and 41071); the Social Insurance Institution of Finland; the Turku University Foundation; Paulo Foundation (Dr Juonala); Paavo Nurmi Foundation (Dr Juonala); Juho Vainio Foundation (Drs Juonala and Pulkki-Raback); Signe and Ane Gyllenberg Foundation (Dr Pulkki-Raback); Sigrid Juselius Foundation (Dr Juonala); Maud Kuistila Foundation (Dr Juonala); research funds from the Kuopio, Turku, and Tampere University Hospitals; the Finnish Foundation of Cardiovascular Research (Dr Juonala); the Finnish Medical Foundation (Dr Juonala); the Orion-Farmos Research Foundation; the Finnish Cultural Foundation and the Bothnia Welfare Coalition for Research and Knowledge through grants from the Regional Council of Ostrobothnia; the Vaasa Hospital District; the City of Vaasa; the University of Vaasa; and European Regional Development Fund (Dr Pulkki-Raback). Dr Magnussen holds a National Health and Medical Research Council Early Career Fellowship (APP1037559). Dr Sabin holds a National Health and Medical Research Council Health Professional Training Fellowship (APP1012201). Dr Burgner holds a National Health and Medical Research Council Senior Research Fellowship (APP1064629) and an honorary National Heart Foundation Future Leader Fellowship (100369). Dr Hare holds a National Health and Medical Research Council Practitioner Fellowship (APP628399). Research at Murdoch Childrens Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program.